Keda tänada napi pääsemise eest? Järeldusi ühest 1796. aastal toimunud riskantsest mereretkest Vormsilt ja Noarootsist Soome
نویسندگان
چکیده
منابع مشابه
Dmd052514 1787..1796
Failure in amyloid-b (Ab) systemic clearance across the liver has been suggested to play a role in Ab brain accumulation and thus to contribute largely to the pathology of Alzheimer’s disease (AD). The purpose of this study was to characterize in vitro the transport mechanisms of Ab40 across the liver using sandwich-cultured primary rat hepatocytes (SCHs) and to determine its biliary clearance ...
متن کاملDmd060194 1796..1802
CYP3A5 plays a prominent role in the metabolism of maraviroc, an approved drug for human immunodeficiency virus (HIV)-1 treatment and a candidate for HIV-1 prevention. We studied the effect of the CYP3A5 genotype on pharmacokinetics of maraviroc and a primary CYP3A5-dependent metabolite of maraviroc denoted as metabolite 1 (M1). Volunteers were screened for health status and CYP3A5 genotype (wi...
متن کاملWiltshire Coroners' Bills 1752–1796
absence of any restraint upon the author's curiosity by the need to attend to a specific problem. This author is indeed inquisitive: he exploits analogies from all the natural world to explain physiological processes, and he is probably the first person known to have modified an existing object to make an apparatus for use in demonstration. Analogical reasoning and experiment loom large in thes...
متن کاملPhosphophloretin sensitivity of rabbit renal NaPi-IIa and NaPi-Ia.
The effect of phosphorylated phloretins on Na(+)-dependent phosphate uptake into rabbit renal brush-border membrane vesicles (BBMV) was examined. Na(+)-dependent phosphate uptake into isolated rabbit cortex BBMV was sensitive to 2'-phosphophloretin (2'-PP) and 2'-phospho-4',4,6'-trimethoxy phloretin (PTMP) in a dose-dependent and pH-dependent manner. PTMP inhibition of Na(+)-dependent phosphate...
متن کاملNaPi-IIa and interacting partners.
Regulation of renal proximal tubular reabsorption of phosphate (Pi) is one of the critical steps in Pi homeostasis. Experimental evidence suggests that this regulation is achieved mainly by controlling the apical expression of the Na+-dependent Pi cotransporter type IIa (NaPi-IIa) in proximal tubules. Only recently have we started to obtain information regarding the molecular mechanisms that co...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Mäetagused
سال: 2004
ISSN: 1406-992X,1406-9938
DOI: 10.7592/mt2004.27.beyer